PNE took a 3-0 lead at half time with goals from Sam Osobe, Ryan Croasdale and Matt Dudley, further strikes in the second half from Luke Clark and Jack Sowerby completed the 5-0 victory.
Carlisle lead the table on 24 points from 11 matches after a 3-1 win at home to Accrington.
Only goal difference seperates the leaders from Burnley after the Clarets 2-1 win at home to Oldham.
The Lilywhites are third and Walsall drop to fourth after their 0-0 draw at home to lowly Wigan which saw them lose their 100% record and now have 22 points from 8 matches.
Bury are fifth with 19 points from 11 matches and Tranmere are sixth with 18 points from 11 matches after their 4-0 home defeat against Wrexham.